SF1670

Catalog No.: A13475

PTEN inhibitor

SF1670

SF1670 Chemical Structure

CAS NO. 345630-40-2

SF1670 is a selective PTEN inhibitor (IC50=2 uM). As PTEN-mTOR pathway is critical for controlling the regenerative capacity of corticospinal neurons, PTEN deletion or its inhibitor enhances the regenerative ability of adult corticospinal neurons. Pretreatment with SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model.

Availability: In stock

Package Price Qty
5 mg
$108.00
10 mg
$184.00
25 mg
$324.00
50 mg
$540.00
10mM * 1mL in DMSO
$110.00
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Biological Activity

SF1670 is a selective PTEN inhibitor (IC50=2 uM). As PTEN-mTOR pathway is critical for controlling the regenerative capacity of corticospinal neurons, PTEN deletion or its inhibitor enhances the regenerative ability of adult corticospinal neurons. Pretreatment with SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model.
Targets
PTEN
2 μM
In vitro DMSO 29 mg/mL heating (94.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL heating (3.25 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.53 mL 162.65 mL 325.31 mL
0.5 mM 6.51 mL 32.53 mL 65.06 mL
1 mM 3.25 mL 16.27 mL 32.53 mL
5 mM 0.65 mL 3.25 mL 6.51 mL

*The above data is based on the productmolecular weight 307.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13475
Actions Inhibitor
M. Wt 307.4
Formula C19H17NO3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 345630-40-2
Synonyms SF 1670, SF-1670
SMILES CC(C)(C)C(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C(=O)C2=O

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