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|Storage||at -20°C 3 years Powder|
|Synonyms||SF 1670, SF-1670|
|SF1670 is a selective PTEN inhibitor (IC50=2 uM). As PTEN-mTOR pathway is critical for controlling the regenerative capacity of corticospinal neurons, PTEN deletion or its inhibitor enhances the regenerative ability of adult corticospinal neurons. Pretreatment with SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model.|
|Solubility (25°C)*||In vitro||DMSO||29 mg/mL heating (94.35 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||1 mg/mL heating (3.25 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||32.53 mL||162.65 mL||325.31mL|
|0.5 mM||6.51 mL||32.53 mL||65.06 mL|
|1 mM||3.25 mL||16.27 mL||32.53 mL|
|5 mM||0.65 mL||3.25 mL||6.51 mL|
*The above data is based on the productmolecular weight 307.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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