Sirtuins

Catalog No.Inhibitor Name SIRT1SIRT2SIRT3SirtuinOther
A10377Selisistat (EX 527)
****
A12226Sirtinol
*
**
A15902SirReal2
****
A14221Splitomicin
**
A14225AGK2
***
A12305Tenovin-6
***
*
p53

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Tenovin-6

    Catalog No. A12305
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    p53 activator
    Tenovin-6 is a analog of tenovin-1. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 values of 21, 10, and 67 uM, respectively. Learn More

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