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Skepinone-L

Catalog No.: A11321
p38 MAPK inhibitor
Adooq's Skepinone-L has been cited by 1 publications
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
Skepinone-L
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
2mg
$35.00
In stock
5mg
$65.00
In stock
10mg
$115.00
In stock
25mg
$205.00
In stock
50mg
$315.00
In stock
100mg
$455.00
In stock
10mM * 1mL in DMSO
$70.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Skepinone-L has been cited by 1 publications
  • Ramona Rudalska, etc. In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer. Nat Med. 2014 Oct; 20(10): 1138?€?1146.
    • Biological Activity
    Discription Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
    Targets
    Target Value
    Product Information
    Catalog Num A11321
    Formula C24H21F2NO4
    Molecular Weight 425.42
    CAS Number 1221485-83-1
    SMILES C1CC2=C(C=CC(=C2)NC3=C(C=C(C=C3)F)F)C(=O)C4=C1C=CC(=C4)OC[C@@H](CO)O
    Synonyms Skepinone L
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 81 mg/mL (190.4 mM)
    Water Insoluble
    Ethanol 81 mg/mL (190.4 mM)
    In vivo 0.5% methylcellulose 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.51 mL 117.53 mL 235.06 mL
    0.5 mM 4.7 mL 23.51 mL 47.01 mL
    1 mM 2.35 mL 11.75 mL 23.51 mL
    5 mM 0.47 mL 2.35 mL 4.7 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    MAPK > p38-MAPK
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