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p38 MAPK inhibitor

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Catalog No. A11321

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Skepinone-L 2mg A11321-2

Regular Price: $120.00

Special Price: $108.00

Skepinone-L 5mg A11321-5

Regular Price: $240.00

Special Price: $216.00

Skepinone-L 10mg A11321-10

Regular Price: $400.00

Special Price: $360.00

Skepinone-L 25mg A11321-25

Regular Price: $800.00

Special Price: $720.00

Skepinone-L 10mM * 1mL in DMSO A11321-10mM-D

Regular Price: $314.00

Special Price: $282.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.


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Chemical Information

Catalog Num A11321
Actions Inhibitor
M. Wt 425.42
Formula C24H21F2NO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1221485-83-1
Synonyms Skepinone L
SMILES C1CC2=C(C=CC(=C2)NC3=C(C=C(C=C3)F)F)C(=O)C4=C1C=CC(=C4)OC[[email protected]@H](CO)O

Biological Activity

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
5 nM


Solubility (25°C) * In vitro DMSO 85 mg/mL (199.8 mM)
Water <1 mg/mL (<1 mM)
Ethanol 85 mg/mL (199.8 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.51 mL 117.53 mL 235.06mL
0.5 mM 4.7 mL 23.51 mL 47.01 mL
1 mM 2.35 mL 11.75 mL 23.51 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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