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Skepinone-L Chemical Structure

CAS NO. 1221485-83-1

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.

Availability: In stock

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2 mg
5 mg
10 mg
25 mg
10mM * 1mL in DMSO
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Biological Activity

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
5 nM
In vitro (25°C) DMSO 81 mg/mL (190.4 mM)
Water Insoluble
Ethanol 81 mg/mL (190.4 mM)
In vivo 0.5% methylcellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.51 mL 117.53 mL 235.06 mL
0.5 mM 4.7 mL 23.51 mL 47.01 mL
1 mM 2.35 mL 11.75 mL 23.51 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11321
Actions Inhibitor
CAS No. 1221485-83-1
Formula C24H21F2NO4
M. Wt 425.42
Purity >98%
Synonyms Skepinone L
SMILES C1CC2=C(C=CC(=C2)NC3=C(C=C(C=C3)F)F)C(=O)C4=C1C=CC(=C4)OC[[email protected]@H](CO)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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