SKF 86002 Dihydrochloride

Catalog No.: A11101

p38 MAPK inhibitor

SKF 86002 Dihydrochloride Chemical Structure

CAS NO. 116339-68-5

SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM).

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$180.00
50 mg
$800.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.01 mL 135.04 mL 270.07 mL
0.5 mM 5.4 mL 27.01 mL 54.01 mL
1 mM 2.7 mL 13.5 mL 27.01 mL
5 mM 0.54 mL 2.7 mL 5.4 mL

*The above data is based on the productmolecular weight 370.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11101
Actions Inhibitor
M. Wt 370.27
Formula C16H12FN3S.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 116339-68-5
Synonyms SKF86002 Dihydrochloride
SMILES C1CSC2=NC(=C(N21)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl.Cl

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