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SKF 86002 Dihydrochloride

p38 MAPK inhibitor

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Catalog No. A11101

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SKF 86002 Dihydrochloride 5mg A11101-5
SKF 86002 Dihydrochloride 10mg A11101-10
SKF 86002 Dihydrochloride 50mg A11101-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM).

SKF 86002 Dihydrochloride

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Chemical Information

Catalog Num A11101
Actions Inhibitor
M. Wt 370.27
Formula C16H12FN3S.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 116339-68-5
Synonyms SKF86002 Dihydrochloride

Biological Activity

SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.01 mL 135.04 mL 270.07mL
0.5 mM 5.4 mL 27.01 mL 54.01 mL
1 mM 2.7 mL 13.5 mL 27.01 mL
5 mM 0.54 mL 2.7 mL 5.4 mL

*The above data is based on the productmolecular weight 370.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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