StemRegenin 1 (SR1)

Catalog No.: A12945

AhR antagonist

StemRegenin 1 (SR1)

StemRegenin 1 (SR1) Chemical Structure

CAS NO. 1227633-49-9

StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$100.00
50 mg
$160.00
100 mg
$270.00
10mM * 1mL in DMSO
$87.00
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Biological Activity

StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).
Targets
Aryl hydrocarbon receptor (AhR) ()
127 nM
In vitro DMSO 84 mg/mL (195.55 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.46 mL 107.3 mL 214.59 mL
0.5 mM 4.29 mL 21.46 mL 42.92 mL
1 mM 2.15 mL 10.73 mL 21.46 mL
5 mM 0.43 mL 2.15 mL 4.29 mL

*The above data is based on the productmolecular weight 466. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12945
Actions Antagonist
CAS No. 1227633-49-9
Formula C24H23N5OS?HCl
M. Wt 466
Solubility DMSO
Purity >98%
Synonyms SR-1
SMILES CC(C)N1C=NC2=C1N=C(N=C2NCCC3=CC=C(C=C3)O)C4=CSC5=CC=CC=C54
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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