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$0.00 Biological Activity
StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).
Targets
| Aryl hydrocarbon receptor (AhR) () | ||||
| 127 nM |
| In vitro | DMSO | 86 mg/mL (200.21 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.46 mL | 107.3 mL | 214.59 mL |
| 0.5 mM | 4.29 mL | 21.46 mL | 42.92 mL |
| 1 mM | 2.15 mL | 10.73 mL | 21.46 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.29 mL |
*The above data is based on the productmolecular weight 466. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A12945 |
|---|---|
| Actions | Antagonist |
| M. Wt | 466 |
| Formula | C24H23N5OS?HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1227633-49-9 |
| Synonyms | SR-1 |
| SMILES | CC(C)N1C=NC2=C1N=C(N=C2NCCC3=CC=C(C=C3)O)C4=CSC5=CC=CC=C54 |
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