STF-62247

Catalog No.: A10866
Autophagy Inducer
STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).
Grouped product items
Product Name Price Stock Qty
STF-62247 10mg
$50.00
In stock
STF-62247 25mg
$110.00
In stock
STF-62247 50mg
$190.00
In stock
STF-62247 100mg
$350.00
In stock
STF-62247 10mM * 1mL in DMSO
$50.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).
Product Information
Catalog Num A10866
Formula C15H13N3S
Molecular Weight 267.4
CAS Number 315702-99-9
SMILES CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3
Synonyms STF62247
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 47 mg/mL (175.8 mM)
Water Insoluble
Ethanol 3 mg/mL (11.22 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.4 mL 186.99 mL 373.97 mL
0.5 mM 7.48 mL 37.4 mL 74.79 mL
1 mM 3.74 mL 18.7 mL 37.4 mL
5 mM 0.75 mL 3.74 mL 7.48 mL
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