STF-62247

Catalog No.: A10866

Autophagy Inducer

STF-62247

STF-62247 Chemical Structure

CAS NO. 315702-99-9

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $50.00

Special Price $45.00

25 mg

Regular Price: $110.00

Special Price $99.00

50 mg

Regular Price: $190.00

Special Price $171.00

100 mg

Regular Price: $350.00

Special Price $315.00

10mM * 1mL in DMSO

Regular Price: $50.00

Special Price $45.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).
Targets
In vitro (25°C) DMSO 53 mg/mL (198.24 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.22 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.4 mL 186.99 mL 373.97 mL
0.5 mM 7.48 mL 37.4 mL 74.79 mL
1 mM 3.74 mL 18.7 mL 37.4 mL
5 mM 0.75 mL 3.74 mL 7.48 mL

*The above data is based on the productmolecular weight 267.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10866
Actions Inducer
M. Wt 267.4
Formula C15H13N3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 315702-99-9
Synonyms STF62247
SMILES CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3

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