Total item
Cart Subtotal
$0.00 Biological Activity
T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2.
Targets
| PPARγ (Cell-free assay) | PPARα (Cell-free assay) | PPARδ (Cell-free assay) | ||
| 1 nM | 0.85 μM | 1.8 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.02 mL | 180.08 mL | 360.15 mL |
| 0.5 mM | 7.2 mL | 36.02 mL | 72.03 mL |
| 1 mM | 3.6 mL | 18.01 mL | 36.02 mL |
| 5 mM | 0.72 mL | 3.6 mL | 7.2 mL |
*The above data is based on the productmolecular weight 277.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11588 |
|---|---|
| Actions | Antagonist |
| M. Wt | 277.66 |
| Formula | C12H8ClN3O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 313516-66-4 |
| Synonyms | T 0070907 |
| SMILES | ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=CC=NC=C2)=O |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy T0070907 | T0070907 Supplier | purchase | cost | manufacturer | order | distributor | buy 313516-66-4| 313516-66-4 Supplier | purchase 313516-66-4 | 313516-66-4 cost | 313516-66-4 manufacturer | order 313516-66-4 | 313516-66-4 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.