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Publications citing Adooq Products
Chemical Information
| Catalog Num | A11588 |
|---|---|
| Actions | Antagonist |
| M. Wt | 277.66 |
| Formula | C12H8ClN3O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 313516-66-4 |
| Synonyms | T 0070907 |
| SMILES | ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=CC=NC=C2)=O |
Description |
T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2. | ||||||||||
Targets |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.02 mL | 180.08 mL | 360.15mL |
| 0.5 mM | 7.2 mL | 36.02 mL | 72.03 mL |
| 1 mM | 3.6 mL | 18.01 mL | 36.02 mL |
| 5 mM | 0.72 mL | 3.6 mL | 7.2 mL |
*The above data is based on the productmolecular weight 277.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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