Subscribe to Feed

Products tagged with 'Akt1'

5 Item(s)

per page

Set Descending Direction
  1. AKT inhibitor VIII (AKTI-1/2)

    Catalog No. A11286
    Quick View
    AKT inhibitor
    AKT inhibitor VIII is a cell-permeable and reversible quinoxaline compound that potently and selectively inhibits Akt1/Akt2 activity (IC50 = 58 nM, 210 nM, and 2.12 μM for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays). Learn More
  2. AZD5363

    Catalog No. A11759
    Quick View
    AKT inhibitor
    AZD5363 is a potent inhibitor of AKT with pharmacodynamic activity in vivo, has potential to treat a range of solid and hematologic tumors as monotherapy or a combinatorial agent. Learn More
  3. GDC-0068 (Ipatasertib, RG-7440)

    Catalog No. A11246
    Quick View
    Akt Inhibitor
    GDC-0068 is a selective, ATP-competitive, pan-Akt inhibitor that targets Akt1, 2, and 3 with IC50 values of 5, 18, and 8 nM, respectively in cell-free assays Learn More
  4. GSK2141795 (Uprosertib, GSK795)

    Catalog No. A15809
    Quick View
    Akt inhibitor
    Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Learn More
  5. MK-2206 2HCl

    Catalog No. A10003
    Quick View
    AKT Inhibitor
    MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively. Learn More

5 Item(s)

per page

Set Descending Direction
Rewards