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Products tagged with 'ALK'

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  1. ASP3026

    Catalog No. A11773
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    ALK inhibitor
    ASP3026 is a novel and selective inhibitor for the ALK kinase. ASP3026 potently inhibited ALK kinase activity and was more selective than crizotinib in a Tyr-kinase panel. Learn More
  2. AZD3463

    Catalog No. A13065
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    ALK/IGF1R inhibitor
    AZD-3463 is a ALK/IGF1R inhibitor. Learn More
  3. Entrectinib

    Catalog No. A15801
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    TRK, ROS1, ALK inhibitor
    Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity. Learn More
  4. PF-2341066 (Crizotinib)

    Catalog No. A10712
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    ALK/ c-Met inhibitor
    PF-2341066 (Crizotinib) is an inhibitor of the c-Met kinase and the NPM-ALK. PF-2341066 inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM). Learn More
  5. TAE684

    Catalog No. A10662
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    ALK Inhibitor
    TAE684 is a inhibitor of ALK and also a potent inhibitor of LRRK2 kinase activity (IC(50) of 7.8nM against wild-type LRRK2, 6.1nM against the G2019S mutant). Learn More

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