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Products tagged with 'ATM'

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  1. CGK 733

    Catalog No. A13191
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    ATM/ATR inhibitor
    CGK733 is a selective inhibitor of ATR and ATM kinases. Induces cell death in prematurely senescent breast cancer cells. Learn More
  2. CP-466722

    Catalog No. A11086
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    ATM inhibitor
    CP-466722 is a specific ATM inhibitor that inhibits cellular ATM-dependent phosphorylation events and disruption of ATM function resulted in characteristic cell cycle checkpoint defects. Learn More
  3. ETP-46464

    Catalog No. A13328
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    ATR inhibitor
    ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM. Learn More
  4. KU-60019

    Catalog No. A10507
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    ATM Inhibitor
    KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM. Learn More
  5. NU-7441 (KU-57788)

    Catalog No. A11098
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    DNA-PK inhibitor
    NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively. Learn More
  6. NU7026

    Catalog No. A12752
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    DNA-PK inhibitor
    NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia. Learn More
  7. Torin 2

    Catalog No. A11586
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    mTOR inhibitor
    Torin 2 is a potent and selective mTOR inhibitor (IC50 = 2.1 nM). Displays 800-fold cellular selectivity for mTOR over PI3K (cellular EC50 values are 0.25 and 200 nM for mTOR and PI3K respectively). Learn More
  8. VE-822

    Catalog No. A13289
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    ATR inhibitor
    VE-822 is an potent ATR inhibitor. Learn More
  9. Wortmannin

    Catalog No. A11161
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    PI3K inhibitor

    Wortmannin is a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC50 = 2 - 4 nM) which also potently inhibits polo-like kinase 1 (PLK1) (IC50 = 5.8 nM).

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