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Products tagged with 'B-Raf'

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  1. AZ628

    Catalog No. A11063
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    Raf inhibitor
    AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF. Learn More
  2. Dabrafenib (GSK2118436A)

    Catalog No. A11381
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    Raf inhibitor
    Dabrafenib is a potent and selective inhibitor of B-RAF protein kinase carrying V600E mutation, currently in clinical trial. Learn More
  3. GDC-0879

    Catalog No. A10420
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    B-Raf inhibitor
    GDC-0879 is a specific inhibitor of B-Raf kinase enzyme,targeting B-Raf (V600E) (IC50: 0.13 nM). Learn More
  4. RAF265 (CHIR-265)

    Catalog No. A10773
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    RAF/VEGFR Inhibitor
    RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor, which is to control or normalize VEGFR-2 along with the inhibition of B-raf and c-Raf mutation to prevent cancers. Learn More
  5. RO5126766 (CH5126766)

    Catalog No. A14019
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    Raf/MEK dual inhibitor
    RO5126766, also known as CH5126766, is a protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity. Learn More
  6. SB590885

    Catalog No. A10829
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    B-Raf Inhibitor
    SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively. Learn More

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