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Products tagged with 'CDK4'

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  1. AMG-925

    Catalog No. A14025
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    Dual FLT3/CDK4 inhibitor
    AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor. Learn More
  2. BMS-265246

    Catalog No. A11154
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    CDK inhibitor
    BMS-265246 is a potent new pyra- zolopyridine inhibitor of cdk2/cyclin E and cdk1/cyclin B, as well as cdk4/cyclin D. Learn More
  3. Flavopiridol (Alvocidib)

    Catalog No. A10390
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    CDK inhibitor
    Flavopiridol (Alvocidib) is a cyclin-dependent kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia. Learn More
  4. Flavopiridol HCl

    Catalog No. A11045
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    CDK inhibitor
    Flavopiridol HCl is an inhibitor of cyclin-dependent kinases. The (-)-cis form induces apoptosis in particular tumor cells. Learn More
  5. LEE011 (Ribociclib)

    Catalog No. A13549
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    CDK4/6 inhibitor
    LEE011 is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. Learn More
  6. Purvalanol A

    Catalog No. A15517
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    CDK inhibitor
    Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Learn More

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