Subscribe to Feed

Products tagged with 'Chk2'

3 Item(s)

per page

Set Descending Direction
  1. AZD7762

    Catalog No. A10113
    Chk1 & Chk2 inhibitor
    AZD7762 is a potent ATP-competitive checkpoint kinase inhibitor that drives checkpoint abrogation and potentiates DNA-targeted therapies. Learn More
  2. PF 477736

    Catalog No. A11520
    Chk Inhibitor
    PF 477736 is a selective checkpoint kinase 1 (Chk1) inhibitor (Ki values are 0.49 and 47 nM for Chk1 and Chk2 respectively). Learn More
  3. SCH 900776 (MK-8776)

    Catalog No. A11167
    Chk1 inhibitor

    SCH900776 is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. It specifically binds to and inhibits Chk1, which may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases to undergo DNA repair prior to entry into mitosis; tumor cells may thus be sensitized to the DNA-damaging effects of ionizing radiation and alkylating chemotherapeutic agents.

    Learn More

3 Item(s)

per page

Set Descending Direction
Rewards