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Products tagged with 'FGFR1'

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  1. BLU9931

    Catalog No. A15534
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    FGFR inhibitor
    BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM), Learn More
  2. Brivanib alaninate (BMS-582664)

    Catalog No. A10162
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    VEGFR inhibitor
    Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling. Learn More
  3. Debio-1347 (CH5183284)

    Catalog No. A14415
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    FGFR1/2/3 inhibitor
    Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity. Learn More
  4. FIIN-2

    Catalog No. A12357
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    FGFR Inhibitor
    FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively. Learn More
  5. LY 2874455

    Catalog No. A11244
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    FGFR/VEGFR2 inhibitor
    LY2874455 is a novel and potent FGFR/VEGFR Inhibitor. Learn More
  6. SSR128129E

    Catalog No. A13211
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    FGFR1 inhibitor
    SSR128129E is an orally-active and allosteric FGFR1 inhibitor with IC50 of 1.9 uM Learn More
  7. SU-5402

    Catalog No. A11558
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    VEGFR/FGFR/EGFR inhibitor‎
    SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively). Learn More
  8. TSU-68 (Orantinib, SU6668)

    Catalog No. A10953
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    PDFGRβ inhibitor
    Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3. Learn More

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