Subscribe to Feed

Products tagged with 'FLT3'

12 Item(s)

per page

Set Descending Direction
  1. AC220 (Quizartinib)

    Catalog No. A10027
    Quick View
    FLT3 inhibitor
    AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ± 0.3 nM and >10 mM for MC4-11 and A375, respectively. Learn More
  2. AMG-925

    Catalog No. A14025
    Quick View
    Dual FLT3/CDK4 inhibitor
    AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor. Learn More
  3. AZD 2932

    Catalog No. A14156
    Quick View
    mutil-targeted protein tyrosine kinase inhibitor
    AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively. Learn More
  4. Go 6976

    Catalog No. A12419
    PKC inhibitor
    Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3. Learn More
  5. MP470 (MP-470, Amuvatinib)

    Catalog No. A10610
    Quick View
    RTK inhibitor
    MP470 is a c-Kit/PDGFR tyrosine kinase inhibitor. Learn More
  6. Pexidartinib (PLX3397)

    Catalog No. A15520
    Quick View
    CSF1/Kit/FLT3 inhibitor
    Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. Learn More
  7. R406 besylate

    Catalog No. A10769
    Quick View
    Syk Inhibitor
    R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM. Learn More
  8. SGI-1776 (free base)

    Catalog No. A10838
    Quick View
    PIM1 Inhibitor
    SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1. Learn More
  9. TCS 359

    Catalog No. A12427
    Quick View
    FLT3 inhibitor
    TCS 359 is a potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases. Learn More
  10. TG-101348 (Fedratinib, SAR302503)

    Catalog No. A11082
    Quick View
    JAK2 inhibitor
    TG-101348 is an orally bioavailable, ATP-competitive and selective inhibitor of Janus-associated kinase 2 with potential antineoplastic activity. Learn More
  11. TG101209

    Catalog No. A11180
    Quick View
    JAK2 inhibitor

    TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells.

    Learn More
  12. VX-680 (MK-0457, Tozasertib)

    Catalog No. A10981
    Quick View
    Aurora Kinase inhibitor
    VX-680 is a potent and selective small-molecule inhibitor of the Aurora kinases. Learn More

12 Item(s)

per page

Set Descending Direction
Rewards