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Products tagged with 'FXR'

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GW4064

Catalog No. A11141
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FXR agonist

GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM). Learn More

Product Citations (2)

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- Dong-Hyun Kim, .et al. The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD, Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132
- Takae K, .et al. Evidence for the involvement of FXR signaling in ovarian granulosa cell function, J Reprod Dev, 2018, Nov 16 PMID: 30449821
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Lithocholic acid

Catalog No. A12547
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FXR agonist

Lithocholic acid is a bile acid that acts as a detergent to solubilize fats for absorption. Learn More

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Obeticholic Acid

Catalog No. A13866
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FXR agonist

Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM Learn More

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- Tomasz Kostrzewski, .et al. A Microphysiological System for Studying Nonalcoholic Steatohepatitis, Hepatol Commun, 2019, 13 November
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T0901317

Catalog No. A12652
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LXR/FXR agonist

T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively Learn More

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- Tian Yongsong, .et al. Tritium hydrogen-isotope exchange with electron-poor tertiary benzenesulfonamide moiety; application in late-stage labeling of T0901317, J Labelled Comp Radiopharm, 2022, Feb;65(2):36-44 PMID: 34957593
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WAY-362450

Catalog No. A11186
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FXR agonist

WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).
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Product Citations (2)

Bulk Inquiry Free Sample
- Dong-Hyun Kim, .et al. The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD, Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132
- Dong-Hyun Kim, .et al. Src-mediated crosstalk between FXR and YAP protects against renal fibrosis, FASEB J, 2019, Jul 12:fj201900325R PMID: 31298930

Adooq Bioscience

Products tagged with 'FXR'

GW4064

Lithocholic acid

Obeticholic Acid

T0901317

WAY-362450

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