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Products tagged with 'HSP90'

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  1. 17-AAG (KOS953)

    Catalog No. A10010
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    HSP90 inhibitor
    17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90. Learn More
  2. 17-DMAG HCl (Alvespimycin)

    Catalog No. A10011
    Hsp90 inhibitor
    17-DMAG is a water-soluble analog of 17-AAG and geldanamycin that binds the ATP binding site of Hsp90 and inhibits its chaperone activity. Displays more potent antitumor activity than 17-AAG. Learn More
  3. BIIB021

    Catalog No. A10143
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    HSP90 inhibitor
    BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival. Learn More
  4. Ganetespib (STA-9090)

    Catalog No. A11402
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    Hsp90 inhibitor
    Ganetespib is a potent, synthetic, small molecule inhibitor of Hsp90, a chaperone protein that is essential to the function of certain other proteins that drive the growth, proliferation, and survival of many different types of cancer. Learn More
  5. Geldanamycin

    Catalog No. A11025
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    Hsp90 inhibitor
    Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Learn More
  6. KW-2478

    Catalog No. A11195
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    HSP90 inhibitor

    KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

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  7. NMS-E973

    Catalog No. A14292
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    HSP90 inhibitor
    NMS-E973 is a potent and selective Hsp90 inhibitor. Learn More
  8. Onalespib (AT13387)

    Catalog No. A11062
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    HSP90 Inhibitor
    AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Learn More
  9. PF-04929113 (SNX-5422)

    Catalog No. A11074
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    Hsp90 inhibitor
    PF-04929113 (SNX-5422) is orally bioavailable heat shock protein 90 (Hsp90) inhibitor. Learn More
  10. PU-H71

    Catalog No. A11130
    Hsp90 Inhibitor
    PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Learn More
  11. XL-888

    Catalog No. A11251
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    HSP90 Inhibitor
    XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Learn More

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