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Products tagged with 'Microtubules'

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  1. ABT-751 (E-7010)

    Catalog No. A10024
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    Microtubule Associated inhibitor
    ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis. Learn More
  2. Cabazitaxel

    Catalog No. A11831
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    Microtubule Associated inhibitor
    Cabazitaxel is a semi-synthetic derivative of a natural taxoid. Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment Learn More
  3. Cucurbitacin B

    Catalog No. A14665
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    Microtubule polymerization inhibitor
    Cucurbitacin B, a natural triterpenoid is well-known for its strong anticancer activity, and recent studies showed that the compound inhibits JAK/STAT3 pathway. Also it is an potent Microtubule polymerization inhibitor Learn More
  4. CYT997 (Lexibulin)

    Catalog No. A10264
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    Microtubule Inhibitor
    CYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ± 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing. Learn More
  5. Docetaxel (Taxotere)

    Catalog No. A10326
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    Microtubule Associated inhibitor
    Docetaxel (Taxotere) is an antineoplastic agent that acts by disrupting the microtubular network in cells that is essential for mitotic and interphase cellular functions. Learn More
  6. Docetaxel Trihydrate

    Catalog No. A15070
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    Docetaxel trihydrate, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules. Learn More
  7. Ixabepilone

    Catalog No. A11449
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    microtubule inhibitor
    Ixabepilone is an epothilone B analog Learn More
  8. Nocodazole

    Catalog No. A13219
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    microtubule inhibitor
    Nocodazole is a microtubule inhibitor; inhibits mitosis. Also inhibits autophagosome-lysosome fusion. Learn More
  9. Paclitaxel (Taxol)

    Catalog No. A10689
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    Microtubule Associated inhibitor
    Paclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Learn More
  10. Vincristine sulfate

    Catalog No. A10973
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    Tubulin inhibitor
    Vincristine is a mitotic inhibitor, and is used in cancer chemotherapy. Learn More
  11. Vinflunine Tartrate

    Catalog No. A10975
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    Microtubule Associated inhibitor
    Vinflunine Tartrate is a tartrate salt of vinflunine that destabilizes microtubules with an IC50 of 18.8 nM and interferes with the dynamics of microtubules during cell division. Learn More

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