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Products tagged with 'Microtubules'
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ABT-751 (E-7010)
Catalog No. A10024 Microtubule Associated inhibitorABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis. Learn More -
Cabazitaxel
Catalog No. A11831 Microtubule Associated inhibitorCabazitaxel is a semi-synthetic derivative of a natural taxoid. Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment Learn More -
Cucurbitacin B
Catalog No. A14665 Microtubule polymerization inhibitorCucurbitacin B, a natural triterpenoid is well-known for its strong anticancer activity, and recent studies showed that the compound inhibits JAK/STAT3 pathway. Also it is an potent Microtubule polymerization inhibitor Learn More -
CYT997 (Lexibulin)
Catalog No. A10264 Microtubule InhibitorCYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ± 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing. Learn More -
Docetaxel (Taxotere)
Catalog No. A10326 Microtubule Associated inhibitorDocetaxel (Taxotere) is an antineoplastic agent that acts by disrupting the microtubular network in cells that is essential for mitotic and interphase cellular functions. Learn More -
Docetaxel Trihydrate
Catalog No. A15070 Docetaxel trihydrate, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules. Learn More -
Ixabepilone
Catalog No. A11449 microtubule inhibitorIxabepilone is an epothilone B analog Learn More -
Nocodazole
Catalog No. A13219 microtubule inhibitorNocodazole is a microtubule inhibitor; inhibits mitosis. Also inhibits autophagosome-lysosome fusion. Learn More -
Paclitaxel (Taxol)
Catalog No. A10689 Microtubule Associated inhibitorPaclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Learn More -
Vincristine sulfate
Catalog No. A10973 Tubulin inhibitorVincristine is a mitotic inhibitor, and is used in cancer chemotherapy. Learn More -
Vinflunine Tartrate
Catalog No. A10975 Microtubule Associated inhibitorVinflunine Tartrate is a tartrate salt of vinflunine that destabilizes microtubules with an IC50 of 18.8 nM and interferes with the dynamics of microtubules during cell division. Learn More
11 Item(s)
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