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Products tagged with 'OX1 receptor'

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  1. Almorexant HCl

    Catalog No. A14286
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    OX1/OX2 Antagonist
    Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor 3. Learn More
  2. MK-4305 (Suvorexant)

    Catalog No. A11500
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    OX receptor antagonist
    Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia. Learn More
  3. SB-408124

    Catalog No. A11567
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    OX Receptor Antagonist
    SB-408124 is a selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo. Learn More

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