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Products tagged with 'p110δ'

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  1. GDC-0980 (Apitolisib, RG7422)

    Catalog No. A11023
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    mTOR/PI3K Inhibitor
    GDC-0980 (RG7422) is a selective, potent, orally bioavailable inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2) with in vitro IC50 of 5, 27, 7 and 14 nM for p110 α, β, δ and γ isoforms, respectively. Learn More
  2. LY294002

    Catalog No. A10547
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    PI3K Inhibitor
    LY294002 is a PI3k inhibitor (cell IC50 about 10 μM) and a casein kinase II inhibitor. Learn More
  3. PF-4989216

    Catalog No. A12889
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    PI3K inhibitor
    PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110??, p110??, p110??, p110??, and VPS34, respectively. Learn More
  4. PIK-293

    Catalog No. A10727
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    PI3K inhibitor
    PIK-293 is a PI3-K inhibitor. PIK-293 inhibits the p110α, p110β, p110δ. PIK-293 is the parent compound of PIK-294. Learn More
  5. PIK-294

    Catalog No. A10728
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    PI3K inhibitor
    PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported. Learn More
  6. PIK-75

    Catalog No. A10729
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    PI3K Inhibitor
    PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM.2 It inhibits p110γ and p110β considerably less effectively with IC50 values of 0.076 µM and 1.3 µM, respectively. Learn More

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