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Products tagged with 'PI3K'

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  1. Deguelin

    Catalog No. A13460
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    Deguelin is a natural product that displays profound antiproliferative activity. Learn More
  2. GNE-317

    Catalog No. A13992
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    PI3K inhibitor
    GNE-317 is a potent PI3K inhibitor that can cross the Blood brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB. Learn More
  3. Miltefosine

    Catalog No. A14138
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    PI3K/Akt inhibitor
    Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa Learn More
  4. NU-7441 (KU-57788)

    Catalog No. A11098
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    DNA-PK inhibitor
    NU-7441 (KU-57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor. The IC50 values are 14, 1700, 5000, >100000 and >100000 nM for DNA-PK, mTOR, PI 3-K, ATM and ATR respectively. Learn More
  5. NU7026

    Catalog No. A12752
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    DNA-PK inhibitor
    NU7026 is a novel DNA-dependent protein kinase inhibitor that potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia. Learn More
  6. Wortmannin

    Catalog No. A11161
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    PI3K inhibitor

    Wortmannin is a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC50 = 2 - 4 nM) which also potently inhibits polo-like kinase 1 (PLK1) (IC50 = 5.8 nM).

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  7. ZSTK474

    Catalog No. A11014
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    PI3K inhibitor
    ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms. Learn More

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