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Products tagged with 'PI3Kβ'

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  1. AMG319

    Catalog No. A15901
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    PI3Kδ inhibitor
    AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2. Learn More
  2. AS-605240

    Catalog No. A10088
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    PI3K Inhibitor
    AS-605240 is an orally active inhibitor of PI3-kinase γ that inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner with IC50 values of 8, 60, 270, and 300 nM, respectively. Learn More
  3. AZD6482

    Catalog No. A10112
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    PI3K inhibitor
    AZD6482 is a PI3Kbeta inhibitor (IC50=0.021M) used in antithrombotic therapy. Learn More
  4. BAY 80-6946 (Copanlisib)

    Catalog No. A11766
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    PI3K inhibitor
    BAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Learn More
  5. CZC24832

    Catalog No. A11363
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    PI3K inhibitor
    CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay). Learn More
  6. GSK1059615

    Catalog No. A10438
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    mTOR/PI3K Inhibitor
    GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM). Learn More
  7. GSK2636771

    Catalog No. A11784
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    PI3K Inhibitor
    GSK2636771 is a potent, orally bioavailable, PI3K beta-selective inhibitor. Learn More
  8. IC-87114

    Catalog No. A10463
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    PI3K Inhibitor
    IC-87114 was the first isoform-selective PI3K inhibitor :p110M-NM-4(IC50 = 0.13 M-BM-5M) vs. p110M-NM-1(IC50 = 200 M-BM-5M), p110M-NM-2(IC50 = 16 M-BM-5M) and p110M-NM-3(IC50 = 61 M-BM-5M). Learn More
  9. KU 0060648

    Catalog No. A13224
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    DNA-PK inhibitor
    KU0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases. KU-0060648 enhances HDR efficiency and attenuates NHEJ frequency. Learn More
  10. NVP-BGT226

    Catalog No. A11162
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    PI3K inhibitor

    NVP-BGT226, novel phosphoinositide 3-kinase/mTOR dual inhibitor, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo.

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  11. PIK-90

    Catalog No. A10730
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    PI3K Inhibitor
    PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity. Learn More
  12. PKI-402

    Catalog No. A11089
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    PI3K inhibitor
    PKI-402 is a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor. Learn More
  13. TG 100713

    Catalog No. A11956
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    PI3K inhibitor
    TG 100713 is an inhibitor of PI3-kinase that inhibits endothelial cell proliferation. Learn More
  14. TG100-115

    Catalog No. A10922
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    PI3K Inhibitor
    TG100-115 inhibits PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively). Learn More
  15. VS-5584

    Catalog No. A12480
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    PI3K/mTOR inhibitor
    VS-5584 is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Learn More
  16. XL-147 (Pilaralisib)

    Catalog No. A15283
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    PI3K Inhibitor
    XL147 is a potent, orally bioavailable inhibitor of the class I PI3K family of lipid kinases. Learn More
  17. ZSTK474

    Catalog No. A11014
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    PI3K inhibitor
    ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms. Learn More

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