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Products tagged with 'RIP1'

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  1. GSK481

    Catalog No. A12615
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    RIP1 inhibitor
    GSK481 is a novel benzoxazepinone (BOAz) series of RIP1 inhibitors. Receptor Interacting Protein Kinase 1 (RIP1) has been implicated as a key contributor to inflammation through the regulation of programmed necrosis. Inhibition of this kinase has been shown to hinder cell necrotic death, thereby establishing RIP1 as a viable target for the potential treatment of multiple inflammatory diseases. Learn More
  2. Necrostatin-1

    Catalog No. A11973
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    RIPK1 inhibitor
    Necrostatin-1 is an ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM). Learn More

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