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Products tagged with 'VEGFR2'

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  1. AZD 2932

    Catalog No. A14156
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    mutil-targeted protein tyrosine kinase inhibitor
    AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively. Learn More
  2. BMS-794833

    Catalog No. A10154
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    c-Met inhibitor
    BMS-794833 is a potent ATP competitive inhibitor to Met and VEGFR-2 with IC50 of 1.7 and 15 nmol. Learn More
  3. Brivanib alaninate (BMS-582664)

    Catalog No. A10162
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    VEGFR inhibitor
    Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling. Learn More
  4. E-7050 (Golvatinib)

    Catalog No. A11396
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    E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. Learn More
  5. LY 2874455

    Catalog No. A11244
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    FGFR/VEGFR2 inhibitor
    LY2874455 is a novel and potent FGFR/VEGFR Inhibitor. Learn More
  6. PF 477736

    Catalog No. A11520
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    Chk Inhibitor
    PF 477736 is a selective checkpoint kinase 1 (Chk1) inhibitor (Ki values are 0.49 and 47 nM for Chk1 and Chk2 respectively). Learn More
  7. RAF265 (CHIR-265)

    Catalog No. A10773
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    RAF/VEGFR Inhibitor
    RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor, which is to control or normalize VEGFR-2 along with the inhibition of B-raf and c-Raf mutation to prevent cancers. Learn More
  8. SKLB1002

    Catalog No. A13234
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    VEGFR inhibitor
    SKLB1002 is a new potent VEGFR2 inhibitor, which could significantly inhibit HUVEC proliferation, migration, invasion, and tube formation. Learn More
  9. SU-5402

    Catalog No. A11558
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    VEGFR/FGFR/EGFR inhibitor‎
    SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively). Learn More
  10. Telatinib (BAY 57-9352)

    Catalog No. A10903
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    VEGFR-2 inhibitor
    Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases. Learn More
  11. Vandetanib (ZD6474)

    Catalog No. A10963
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    VEGFR inhibitor
    Vandetanib (Zactima) is a VEGFR and EGFR antagonist and a tyrosine kinase inhibitor with IC50 of 60, 90, 40 nM for HUVEC proliferation, PC-9 cells and tyrosine kinase activity, respectively. Learn More

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