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Products tagged with 'XIAP'

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  1. AT-406 (SM-406, ARRY-334543)

    Catalog No. A11163
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    IAP inhibitor
    AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological activity of IAP proteins, including X chromosome-linked IAP (XIAP), the cellular IAPs 1 (c-IAP1) and 2 (c-IAP2) and melanoma inhibitor of apoptosis protein (ML-IAP). Learn More
  2. Birinapant (TL32711)

    Catalog No. A12738
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    XIAP/cIAP1 antagonist
    Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity. Learn More
  3. BV-6

    Catalog No. A14231
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    dual cIAP and XIAP inhibitor
    BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor. Learn More
  4. GDC-0152

    Catalog No. A14135
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    IAP antagonist
    GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity. Learn More
  5. LCL-161

    Catalog No. A11928
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    Antagonist of IAPs inhibitor
    LCL161 is an orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins, with potential antineoplastic activity. Learn More
  6. SM-164

    Catalog No. A15800
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    cIAP-2 antagonist
    SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively. Learn More

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