TAK-438 (vonoprazan)

Catalog No.: A11239

potassium-competitive acid Blocker

TAK-438 (vonoprazan) Chemical Structure

CAS NO. 1260141-27-2

TAK-438 is a novel potassium-competitive acid blocker.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $90.00

Special Price $72.00

5 mg

Regular Price: $150.00

Special Price $120.00

10 mg

Regular Price: $280.00

Special Price $224.00

25 mg

Regular Price: $520.00

Special Price $416.00

10mM * 1mL in DMSO
$267.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TAK-438 is a novel potassium-competitive acid blocker.
Targets
H+/K+-ATPase
19 nM
In vitro (25°C) DMSO 62 mg/mL (134.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 17 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.34 mL 216.68 mL
0.5 mM 4.33 mL 21.67 mL 43.34 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11239
Actions Blocker
M. Wt 461.5
Formula C21H20FN3O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1260141-27-2
Synonyms TAK438
SMILES CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O

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