TAK-438 (vonoprazan)

Catalog No.: A11239

potassium-competitive acid Blocker

TAK-438 (vonoprazan)

TAK-438 (vonoprazan) Chemical Structure

CAS NO. 1260141-27-2

TAK-438 is a novel potassium-competitive acid blocker.

Availability: In stock

Package Price Qty
2 mg
$90.00
5 mg
$150.00
10 mg
$280.00
25 mg
$520.00
10mM * 1mL in DMSO
$267.00
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Biological Activity

TAK-438 is a novel potassium-competitive acid blocker.
Targets
H+/K+-ATPase
19 nM
In vitro (25°C) DMSO 58 mg/mL (125.68 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% methylcellulose 16 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.34 mL 216.68 mL
0.5 mM 4.33 mL 21.67 mL 43.34 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11239
Actions Blocker
CAS No. 1260141-27-2
Formula C21H20FN3O6S
M. Wt 461.5
Purity >98%
Synonyms TAK438
SMILES CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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