Talmapimod (SCIO-469)

Catalog No.: A12770

p38 MAPK inhibitor

Talmapimod (SCIO-469)

Talmapimod (SCIO-469) Chemical Structure

CAS NO. 309913-83-5

Talmapimod (SCIO-469) is a selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro).

Availability: In stock

Package Price Qty
10 mg
$150.00
25 mg
$300.00
50 mg
$500.00
100 mg
$800.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Talmapimod (SCIO-469) is a selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.2 mL 91 mL 182 mL
0.5 mM 3.64 mL 18.2 mL 36.4 mL
1 mM 1.82 mL 9.1 mL 18.2 mL
5 mM 0.36 mL 1.82 mL 3.64 mL

*The above data is based on the productmolecular weight 549.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12770
Actions Inhibitor
M. Wt 549.46
Formula C27H31Cl2FN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 309913-83-5
Synonyms SCIO469, SCIO 469
SMILES C[[email protected]@H]1CN([[email protected]](CN1C(=O)C2=C(C=C3C(=C2)C(=CN3C)C(=O)C(=O)N(C)C)Cl)C)CC4=CC=C(C=C4)F

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