Talmapimod (SCIO-469)

Catalog No.: A12770
p38 MAPK inhibitor
Talmapimod (SCIO-469) is a selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro).
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Talmapimod (SCIO-469) 10mg
Talmapimod (SCIO-469) 25mg
Talmapimod (SCIO-469) 50mg
Talmapimod (SCIO-469) 100mg
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Biological Activity
Discription Talmapimod (SCIO-469) is a selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro).
Target Value
Product Information
Catalog Num A12770
Formula C27H30ClFN4O3.HCl
Molecular Weight 549.46
CAS Number 309915-12-6 (HCl), 309913-83-5
SMILES C[C@@H]1CN([C@H](CN1C(=O)C2=C(C=C3C(=C2)C(=CN3C)C(=O)C(=O)N(C)C)Cl)C)CC4=CC=C(C=C4)F.Cl
Synonyms SCIO469, SCIO 469

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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