Trusted by 10,000+ Scientists since 2006

Tandutinib (MLN518)


FLT3 Inhibitor

158 Customer Reviews
Catalog No. A10887

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Tandutinib 25mg A10887-25

Regular Price: €38.00

Special Price: €34.20

Tandutinib 50mg A10887-50

Regular Price: €47.50

Special Price: €42.75

Tandutinib 100mg A10887-100

Regular Price: €76.00

Special Price: €68.40

Tandutinib 200mg A10887-200

Regular Price: €133.00

Special Price: €119.70

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Tandutinib (MLN518) inhibits the autophosphorylation of FLT3, c-KIT and PDGF receptor tyrosine kinases, thereby inhibiting cellular proliferation and inducing apoptosis.

Tandutinib (MLN518)

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products

Chemical Information

Catalog Num A10887
Actions Inhibitor
M. Wt 562.7
Formula C31H42N6O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 387867-13-2
Synonyms MLN-518, CT53518

Biological Activity

Tandutinib (MLN518) inhibits the autophosphorylation of FLT3, c-KIT and PDGF receptor tyrosine kinases, thereby inhibiting cellular proliferation and inducing apoptosis.
Target Value
c-KitIC50: 0.17μM
PDGFRβIC50: 0.20μM
FLT3IC50: 0.22μM
CSF-1RIC50: 3.43μM
SrcIC50: 30μM
AblIC50: >30μM
PKCIC50: >30μM
PKAIC50: >30μM
MEK1IC50: >30μM
MKK4IC50: >30μM
MKK6IC50: >30μM
ERK2IC50: >30μM
p38IC50: >30μM
KDRIC50: >30μM
EGFRIC50: >30μM
FGFRIC50: >30μM
Insulin ReceptorIC50: >30μM


Solubility (25°C) * In vitro DMSO 5 mg/mL (8.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol 6 mg/mL (10.66 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.77 mL 88.86 mL 177.71mL
0.5 mM 3.55 mL 17.77 mL 35.54 mL
1 mM 1.78 mL 8.89 mL 17.77 mL
5 mM 0.36 mL 1.78 mL 3.55 mL

*The above data is based on the productmolecular weight 562.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Keywords:buy Tandutinib (MLN518) | Tandutinib (MLN518) Supplier | purchase Tandutinib (MLN518) | Tandutinib (MLN518) cost | Tandutinib (MLN518) manufacturer | order Tandutinib (MLN518) | Tandutinib (MLN518) distributor | buy 387867-13-2| 387867-13-2 Supplier | purchase 387867-13-2 | 387867-13-2 cost | 387867-13-2 manufacturer | order 387867-13-2 | 387867-13-2 distributor