Tetrandrine (Fanchinine)

Catalog No.: A10921

Calcium Channel inhibitor

Tetrandrine (Fanchinine)

Tetrandrine (Fanchinine) Chemical Structure

CAS NO. 518-34-3

Tetrandrine is a calcium channel blocker. It inhibits the degranulation of mast cells.Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis.

Availability: In stock

Package Price Qty
100 mg
$35.00
200 mg
$65.00
500 mg
$110.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Tetrandrine is a calcium channel blocker. It inhibits the degranulation of mast cells.Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis.
Targets
Calcium channel
In vitro DMSO 4 mg/mL heating (6.42 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL heating (3.21 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.06 mL 80.28 mL 160.57 mL
0.5 mM 3.21 mL 16.06 mL 32.11 mL
1 mM 1.61 mL 8.03 mL 16.06 mL
5 mM 0.32 mL 1.61 mL 3.21 mL

*The above data is based on the productmolecular weight 622.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10921
Actions Inhibitor
M. Wt 622.8
Formula C38H42N2O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 518-34-3
Synonyms Fanchinine, Hanfangchin A, NSC 77037, S,S-(+)-Tetrandrine, Sinomenine A, TTD, Tetrandrin, d-Tetrandr
SMILES CN1CCC2=CC(=C3C=C2[[email protected]@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[[email protected]]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC

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