Tetrandrine (Fanchinine)

Catalog No.: A10921

Calcium Channel inhibitor

Tetrandrine (Fanchinine)

Tetrandrine (Fanchinine) Chemical Structure

CAS NO. 518-34-3

Tetrandrine is a calcium channel blocker. It inhibits the degranulation of mast cells.Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis.

Availability: In stock

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100 mg

Regular Price: $35.00

Special Price $28.00

200 mg

Regular Price: $65.00

Special Price $52.00

500 mg

Regular Price: $110.00

Special Price $88.00

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Biological Activity

Tetrandrine is a calcium channel blocker. It inhibits the degranulation of mast cells.Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis.
Targets
Calcium channel
In vitro DMSO Warmed: 1 mg/mL (1.6 mM)
Water Insoluble
Ethanol 2 mg/mL (3.21 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.06 mL 80.28 mL 160.57 mL
0.5 mM 3.21 mL 16.06 mL 32.11 mL
1 mM 1.61 mL 8.03 mL 16.06 mL
5 mM 0.32 mL 1.61 mL 3.21 mL

*The above data is based on the productmolecular weight 622.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10921
Actions Inhibitor
CAS No. 518-34-3
Formula C38H42N2O6
M. Wt 622.8
Purity >98%
Synonyms Fanchinine, Hanfangchin A, NSC 77037, S,S-(+)-Tetrandrine, Sinomenine A, TTD, Tetrandrin, d-Tetrandr
SMILES CN1CCC2=CC(=C3C=C2[[email protected]@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[[email protected]]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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