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- Francesca Logiacco, .et al. Microglia sense neuronal activity via GABA in the early postnatal hippocampus, Cell Rep, 2021, Dec 28;37(13):110128 PMID: 34965412
- Saurabh Pandey, .et al. The Post-Synaptic Scaffolding Protein Tamalin Regulates Ligand-Mediated Trafficking of Metabotropic Glutamate Receptors, J Biol Chem, 2020, Jun 19;295(25):8575-8588 PMID: 32376687
- Sharma R, .et al. A Critical Role for Sorting Nexin 1 in the Trafficking of Metabotropic Glutamate Receptors, J Neurosci, 2018, Oct 3;38(40):8605-8620 PMID: 30143569
Biological Activity
Tetrodotoxin is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and muscle action potentials.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.32 mL | 156.61 mL | 313.21 mL |
| 0.5 mM | 6.26 mL | 31.32 mL | 62.64 mL |
| 1 mM | 3.13 mL | 15.66 mL | 31.32 mL |
| 5 mM | 0.63 mL | 3.13 mL | 6.26 mL |
*The above data is based on the productmolecular weight 319.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14533 |
|---|---|
| CAS No. | 4368-28-9 |
| Formula | C11H17N3O8 |
| M. Wt | 319.27 |
| Purity | >98% |
| Synonyms | TTx |
| SMILES | C(C1(C2C3C(N=C(NC34C(C1OC(C4O)(O2)O)O)N)O)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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