TH287

Catalog No.: A15536

MTH1 inhibitor

TH287

TH287 Chemical Structure

CAS NO. 1609960-30-6

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,

Availability: In stock

Package Price Qty
10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $250.00

Special Price $200.00

50 mg

Regular Price: $480.00

Special Price $384.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,
Targets
MTH1 (NUDT1)
0.8 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.16 mL 185.78 mL 371.57 mL
0.5 mM 7.43 mL 37.16 mL 74.31 mL
1 mM 3.72 mL 18.58 mL 37.16 mL
5 mM 0.74 mL 3.72 mL 7.43 mL

*The above data is based on the productmolecular weight 269.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A15536
Actions Inhibitor
M. Wt 269.13
Formula C11H10Cl2N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1609960-30-6
Synonyms TH-287, TH 287
SMILES CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N

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