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MTH1 inhibitor

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Catalog No. A15536

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TH287 10mg A15536-10
TH287 25mg A15536-25
TH287 50mg A15536-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,


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Chemical Information

Catalog Num A15536
Actions Inhibitor
M. Wt 269.13
Formula C11H10Cl2N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1609960-30-6
Synonyms TH-287, TH 287

Biological Activity

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,
0.8 nM

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.16 mL 185.78 mL 371.57mL
0.5 mM 7.43 mL 37.16 mL 74.31 mL
1 mM 3.72 mL 18.58 mL 37.16 mL
5 mM 0.74 mL 3.72 mL 7.43 mL

*The above data is based on the productmolecular weight 269.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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