Thapsigargin

Catalog No.: A14007

SERCA ATPase inhibitor

Thapsigargin

Thapsigargin Chemical Structure

CAS NO. 67526-95-8

Thapsigargin is a cell-permeable sesquiterpene lactone found in the roots of Thapsia garganica. It is a tumor promoter and induces the release of intracellular stored Ca2+ without hydrolysis of inositolphospholipids via inhibition of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50=30 nM).

Availability: Out of stock

Package Price
5 mg
$150.00
10 mg
$250.00
25 mg
$500.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Thapsigargin is a cell-permeable sesquiterpene lactone found in the roots of Thapsia garganica. It is a tumor promoter and induces the release of intracellular stored Ca2+ without hydrolysis of inositolphospholipids via inhibition of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50=30 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.37 mL 76.83 mL 153.67 mL
0.5 mM 3.07 mL 15.37 mL 30.73 mL
1 mM 1.54 mL 7.68 mL 15.37 mL
5 mM 0.31 mL 1.54 mL 3.07 mL

*The above data is based on the productmolecular weight 650.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14007
Actions Inhibitor
M. Wt 650.75
Formula C34H50O12
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 67526-95-8
Synonyms N/A
SMILES CCCCCCCC(=O)O[[email protected]]1[[email protected]]2C(=C([[email protected]@H]1OC(=O)/C(=C\C)/C)C)[[email protected]]3[[email protected]]([[email protected]](C[[email protected]]2(C)OC(=O)C)OC(=O)CCC)([[email protected]](C(=O)O3)(C)O)O

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Thapsigargin | Thapsigargin Supplier | purchase Thapsigargin | Thapsigargin cost | Thapsigargin manufacturer | order Thapsigargin | Thapsigargin distributor | buy 67526-95-8| 67526-95-8 Supplier | purchase 67526-95-8 | 67526-95-8 cost | 67526-95-8 manufacturer | order 67526-95-8 | 67526-95-8 distributor
Rewards