TRP Channel

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  1. TRP agonist

    Evodiamine is a chemical extracted from the Tetradium family of plants. It acts primarily as a thermogenic and stimulant.
  2. TrpA1 channel agonist

    PF-4840154 is a non-electrophilic reference agonist of the TrpA1 channel. The TRPA1 channel is considered an attractive pain target based on the fact that TRPA1 knockout mice showed near complete attenuation of pain behaviors in some pre-clinical development models.
  3. TRPM8 Agonist

    WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 = 193 nM).
  4. TRPM8 agonist

    WS 3 is TRPM8 receptors agonist (EC50 = 3.7 μM) and cooling agent.
  5. TRPA1 agonist

    JT010 is a potent agonist of TRPA1 with an EC50 of 0.65 nM.
  6. TRPM8 agonist

    D-3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity.

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