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Triciribine phosphate (NSC-280594)

Catalog No.: A11033

AKT Inhibitor

Triciribine phosphate (NSC-280594)

Triciribine phosphate (NSC-280594) Chemical Structure

CAS NO. 61966-08-3

Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$130.00
50 mg
$380.00
100 mg
$680.00
10mM * 1mL in DMSO
$85.00
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Biological Activity

Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation.
In vitro (25°C) DMSO 60 mg/mL (187.32 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.98 mL 124.91 mL 249.81 mL
0.5 mM 5 mL 24.98 mL 49.96 mL
1 mM 2.5 mL 12.49 mL 24.98 mL
5 mM 0.5 mL 2.5 mL 5 mL

*The above data is based on the productmolecular weight 400.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11033
Actions Inhibitor
CAS No. 61966-08-3
Formula C13H17N6O7P
M. Wt 400.3
Purity >98%
Synonyms VQD-002,TCN-P
SMILES CN1C2=NC=NC3=C2C(=CN3[[email protected]]4[[email protected]@H]([[email protected]@H]([[email protected]](O4)COP(=O)(O)O)O)O)C(=N1)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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