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Biological Activity
Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation.
In vitro (25°C) | DMSO | 60 mg/mL (187.32 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.98 mL | 124.91 mL | 249.81 mL |
0.5 mM | 5 mL | 24.98 mL | 49.96 mL |
1 mM | 2.5 mL | 12.49 mL | 24.98 mL |
5 mM | 0.5 mL | 2.5 mL | 5 mL |
*The above data is based on the productmolecular weight 400.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11033 |
---|---|
Actions | Inhibitor |
CAS No. | 61966-08-3 |
Formula | C13H17N6O7P |
M. Wt | 400.3 |
Purity | >98% |
Synonyms | VQD-002,TCN-P |
SMILES | CN1C2=NC=NC3=C2C(=CN3[[email protected]]4[[email protected]@H]([[email protected]@H]([[email protected]](O4)COP(=O)(O)O)O)O)C(=N1)N |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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