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$0.00 Biological Activity
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).
| In vitro | DMSO | 100 mg/mL (149.29 mM) | |
| Water | 100 mg/mL (149.29 mM) | ||
| Ethanol | 100 mg/mL (149.29 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.08 mL | 80.4 mL | 160.8 mL |
| 0.5 mM | 3.22 mL | 16.08 mL | 32.16 mL |
| 1 mM | 1.61 mL | 8.04 mL | 16.08 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.22 mL |
*The above data is based on the productmolecular weight 621.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A13194 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 621.9 |
| Formula | C36H59N7O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1320288-17-2 |
| Synonyms | UNC 0646, UNC-0646 |
| SMILES | CC(C)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C5CCCCC5)OC)OCCCN6CCCCC6 |
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