UNC0646

Catalog No.: A13194

G9a/GLP HMTase inhibitor

UNC0646

UNC0646 Chemical Structure

CAS NO. 1320288-17-2

UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).

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10 mg

Regular Price: $100.00

Special Price $80.00

25 mg

Regular Price: $200.00

Special Price $160.00

50 mg

Regular Price: $350.00

Special Price $280.00

100 mg

Regular Price: $600.00

Special Price $480.00

10mM * 1mL in DMSO

Regular Price: $80.00

Special Price $64.00

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Biological Activity

UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).
In vitro DMSO 31 mg/mL (49.84 mM)
Water Insoluble
Ethanol 47 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.08 mL 80.4 mL 160.8 mL
0.5 mM 3.22 mL 16.08 mL 32.16 mL
1 mM 1.61 mL 8.04 mL 16.08 mL
5 mM 0.32 mL 1.61 mL 3.22 mL

*The above data is based on the productmolecular weight 621.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13194
Actions Inhibitor
CAS No. 1320288-17-2
Formula C36H59N7O2
M. Wt 621.9
Purity >98%
Synonyms UNC 0646, UNC-0646
SMILES CC(C)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C5CCCCC5)OC)OCCCN6CCCCC6
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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