UNC0646

Catalog No.: A13194

G9a/GLP HMTase inhibitor

UNC0646

UNC0646 Chemical Structure

CAS NO. 1320288-17-2

UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $100.00

Special Price $90.00

25 mg

Regular Price: $200.00

Special Price $180.00

50 mg

Regular Price: $350.00

Special Price $315.00

100 mg

Regular Price: $600.00

Special Price $540.00

10mM * 1mL in DMSO

Regular Price: $80.00

Special Price $72.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).
In vitro DMSO 100 mg/mL (149.29 mM)
Water 100 mg/mL (149.29 mM)
Ethanol 100 mg/mL (149.29 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.08 mL 80.4 mL 160.8 mL
0.5 mM 3.22 mL 16.08 mL 32.16 mL
1 mM 1.61 mL 8.04 mL 16.08 mL
5 mM 0.32 mL 1.61 mL 3.22 mL

*The above data is based on the productmolecular weight 621.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13194
Actions Inhibitor
M. Wt 621.9
Formula C36H59N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1320288-17-2
Synonyms UNC 0646, UNC-0646
SMILES CC(C)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C5CCCCC5)OC)OCCCN6CCCCC6

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