Vatalanib (PTK787) 2HCl

Vatalanib (PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis that inhibits all known VEGF receptors, as well as platelet-derived growth factor receptor-beta and c-kit, but is most selective for VEGFR-2. CAS: 212141-51-0 (HCl) 212141-54-3 (Free base)
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Product Name Price Stock Qty
Vatalanib 10mg
$40.00
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Vatalanib 50mg
$75.00
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Vatalanib 100mg
$120.00
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Vatalanib (PTK787) 2HCl 10mM * 1mL in DMSO
$55.00
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Adooq Products cited in reputable paper
Adooq's Vatalanib (PTK787) 2HCl has been cited by 1 publications
  • Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932
  • Biological Activity
    Discription Vatalanib (PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis that inhibits all known VEGF receptors, as well as platelet-derived growth factor receptor-beta and c-kit, but is most selective for VEGFR-2. CAS: 212141-51-0 (HCl) 212141-54-3 (Free base)
    Targets
    Target Value
    Product Information
    Catalog Num A10967
    Formula C20H17Cl3N4
    Molecular Weight 419.7
    CAS Number 212141-51-0
    SMILES C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl
    Synonyms Vatalanib,PTK787,PTK/ZK
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 77 mg/mL (183.45 mM)
    Water 9 mg/mL (21.44 mM)
    Ethanol 5 mg/mL (11.91 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.83 mL 119.13 mL 238.27 mL
    0.5 mM 4.77 mL 23.83 mL 47.65 mL
    1 mM 2.38 mL 11.91 mL 23.83 mL
    5 mM 0.48 mL 2.38 mL 4.77 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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