Vinorelbine (Navelbine)

Catalog No.: A10976

Vinorelbine (Navelbine)

Vinorelbine (Navelbine) Chemical Structure

CAS NO. 71486-22-1

Vinorelbine is the first 5´NOR semi-synthetic vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periwinkle, Catharanthus roseus.

Availability: In stock

Package Price Qty
10 mg
$60.00
25 mg
$110.00
50 mg
$180.00
100 mg
$300.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Roma Kaul, .et al. Eribulin rapidly inhibits TGF-β-induced Snail expression and can induce Slug expression in a Smad4-dependent manner, Br J Cancer, 2019, 121, pages611–621 PMID: 31481735
  • Nicholas F. Dybdal-Hargreaves, .et al. Regulation of E-cadherin localization by microtubule targeting agents: rapid promotion of cortical E-cadherin through p130Cas/Src inhibition by eribulin, Oncotarget, 2018, Jan 19; 9(5): 5545–5561 PMID: 29464017
  • APRIL L. RISINGER, .et al. Breast Cancer Cell Lines Exhibit Differential Sensitivities to Microtubule-targeting Drugs Independent of Doubling Time, Anticancer Res, 2015, Nov; 35(11): 5845–5850. PMID: 26504006

Biological Activity

Vinorelbine is the first 5´NOR semi-synthetic vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periwinkle, Catharanthus roseus.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.84 mL 64.19 mL 128.39 mL
0.5 mM 2.57 mL 12.84 mL 25.68 mL
1 mM 1.28 mL 6.42 mL 12.84 mL
5 mM 0.26 mL 1.28 mL 2.57 mL

*The above data is based on the productmolecular weight 778.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10976
M. Wt 778.9
Formula C45H54N4O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 71486-22-1
SMILES CCC1=C[[email protected]]2C[[email protected]@](C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[[email protected]]78CCN9[[email protected]]7[[email protected]@](C=CC9)([[email protected]]([[email protected]@]([[email protected]@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy Vinorelbine (Navelbine) | Vinorelbine (Navelbine) Supplier | purchase | cost | manufacturer | order | distributor | buy 71486-22-1| 71486-22-1 Supplier | purchase 71486-22-1 | 71486-22-1 cost | 71486-22-1 manufacturer | order 71486-22-1 | 71486-22-1 distributor
Rewards