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|Storage||at -20°C 3 years Powder|
|Chemical Name||3-(3,4-Difluorobenzoyl)-1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester|
WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).
|Solubility (25°C) *||In vitro||DMSO||33 mg/mL (75.26 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||2 mg/mL (4.56 mM)|
|In vivo||NMP/polyethylene glycol 300 (10/90, v/v)||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||22.81 mL||114.03 mL||228.07mL|
|0.5 mM||4.56 mL||22.81 mL||45.61 mL|
|1 mM||2.28 mL||11.4 mL||22.81 mL|
|5 mM||0.46 mL||2.28 mL||4.56 mL|
*The above data is based on the productmolecular weight 438.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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