WAY-362450

Catalog No.: A11186

FXR agonist

WAY-362450

WAY-362450 Chemical Structure

CAS NO. 629664-81-9

WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $81.00

10 mg

Regular Price: $150.00

Special Price $135.00

50 mg

Regular Price: $480.00

Special Price $432.00

100 mg

Regular Price: $780.00

Special Price $702.00

10mM * 1mL in DMSO

Regular Price: $100.00

Special Price $90.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).

Targets
FXR
4 nM(EC50)
In vitro (25°C) DMSO 33 mg/mL (75.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.56 mM)
In vivo NMP/polyethylene glycol 300 (10/90, v/v) 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.81 mL 114.03 mL 228.07 mL
0.5 mM 4.56 mL 22.81 mL 45.61 mL
1 mM 2.28 mL 11.4 mL 22.81 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11186
Actions Agonist
M. Wt 438.47
Formula C25H24F2N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 629664-81-9
Synonyms WAY362450, XL335
SMILES CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F

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