Signaling Pathway
WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).
Important Notice: For research use only. We do not sell to patients.
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| Discription | WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%). |
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| Catalog Num | A11186 |
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| Formula | C25H24F2N2O3 |
| Molecular Weight | 438.47 |
| CAS Number | 629664-81-9 |
| SMILES | CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F |
| Synonyms | WAY362450, XL335 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 31 mg/mL (70.7 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (4.56 mM) | ||
| In vivo | NMP+PEG300 (10+90, v+v) | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.81 mL | 114.03 mL | 228.07 mL |
| 0.5 mM | 4.56 mL | 22.81 mL | 45.61 mL |
| 1 mM | 2.28 mL | 11.4 mL | 22.81 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
