Total item
Cart Subtotal
$0.00 Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
Biological Activity
WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).
Targets
| mTOR | ||||
| 0.19 nM |
| In vitro (25°C) | DMSO | 95 mg/mL (182.83 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.25 mL | 96.23 mL | 192.46 mL |
| 0.5 mM | 3.85 mL | 19.25 mL | 38.49 mL |
| 1 mM | 1.92 mL | 9.62 mL | 19.25 mL |
| 5 mM | 0.38 mL | 1.92 mL | 3.85 mL |
*The above data is based on the productmolecular weight 519.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11038 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1144068-46-1 |
| Formula | C27H33N7O4 |
| M. Wt | 519.6 |
| Purity | >98% |
| Synonyms | WYE125132, WYE-132, WYE132 |
| SMILES | CNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCC5(CC4)OCCO5)C(=N2)N6CC7CCC(C6)O7 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy WYE-125132 (WYE-132) | WYE-125132 (WYE-132) Supplier | purchase | cost | manufacturer | order | distributor | buy 1144068-46-1| 1144068-46-1 Supplier | purchase 1144068-46-1 | 1144068-46-1 cost | 1144068-46-1 manufacturer | order 1144068-46-1 | 1144068-46-1 distributor
Adooq Quality Guarantee
We promise all products perform as described.