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WZ8040

Catalog No.: A10992

EGFR Inhibitor

WZ8040

WZ8040 Chemical Structure

CAS NO. 1214265-57-2

WZ8040 is a novel EGFR inhibitors that suppress the growth of EGFR-T790M-containing cell lines and inhibit EGFR phosphorylation.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
50 mg
$450.00
100 mg
$750.00
10mM * 1mL in DMSO
$126.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

WZ8040 is a novel EGFR inhibitors that suppress the growth of EGFR-T790M-containing cell lines and inhibit EGFR phosphorylation.
Targets
EGFR (T790M)
In vitro DMSO 86 mg/mL (178.79 mM)
Water Insoluble
Ethanol 3 mg/mL (6.23 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.79 mL 103.95 mL 207.9 mL
0.5 mM 4.16 mL 20.79 mL 41.58 mL
1 mM 2.08 mL 10.4 mL 20.79 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 481.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10992
Actions Inhibitor
CAS No. 1214265-57-2
Formula C24H25ClN6OS
M. Wt 481.0
Purity >98%
Synonyms WZ-8040
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)SC4=CC=CC(=C4)NC(=O)C=C)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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