Total item
Cart Subtotal
$0.00 Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
Biological Activity
WZ8040 is a novel EGFR inhibitors that suppress the growth of EGFR-T790M-containing cell lines and inhibit EGFR phosphorylation.
Targets
| EGFR (T790M) | ||||
| In vitro | DMSO | 86 mg/mL (178.79 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (6.23 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.79 mL | 103.95 mL | 207.9 mL |
| 0.5 mM | 4.16 mL | 20.79 mL | 41.58 mL |
| 1 mM | 2.08 mL | 10.4 mL | 20.79 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.16 mL |
*The above data is based on the productmolecular weight 481.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10992 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1214265-57-2 |
| Formula | C24H25ClN6OS |
| M. Wt | 481.0 |
| Purity | >98% |
| Synonyms | WZ-8040 |
| SMILES | CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)SC4=CC=CC(=C4)NC(=O)C=C)Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Canertinib (CI-1033)
Canertinib (CI-1033) is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (I…
Mubritinib (TAK 165)
Mubritinib (TAK 165) is a potent EGFR and p34cdc2 inhibitor with IC50 of 6 nM and 0.2 µM, respectively. Mubritinib(TAK 165) also inhibits p…
AG-18 (Tyrphostin 23)
AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 ,M in the human epidermoid carcinoma cell li…
WZ3146
WZ3146 is an inhibitor of EGFR receptor kinase mutants carrying a mutation in an active site gatekeeper residue (T790M) and is much less pot…
ARRY-543 (Varlitinib, ASLAN001)
ARRY-543 is a novel, oral ErbB family inhibitor that, unlike approved ErbB inhibitors, targets all members of the ErbB family, including Erb…
Pelitinib (EKB-569)
Pelitinib (EKB-569) is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity.
XL647 (Tesevatinib)
XL647 is an orally bioavailable small-molecule RTK inhibitor that binds to and inhibits several tyrosine receptor kinases that play major ro…
ASP8273 (Naquotinib)
ASP8273 is an orally available, irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with po…
Keywords:buy WZ8040 | WZ8040 Supplier | purchase | cost | manufacturer | order | distributor | buy 1214265-57-2| 1214265-57-2 Supplier | purchase 1214265-57-2 | 1214265-57-2 cost | 1214265-57-2 manufacturer | order 1214265-57-2 | 1214265-57-2 distributor
Adooq Quality Guarantee
We promise all products perform as described.