YK 4-279

Name: YK 4-279
SKU: A11612
Price: 60 USD
Rating: 5 (1 reviews)

Catalog No.: A11612

RHA inhibitor

Adooq's YK 4-279 has been cited by 1 publications

YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1.

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's YK 4-279 has been cited by 1 publications

Christopher M Schafer, .et al. , Proc Natl Acad Sci U S A, 2020, Oct 20;117(42):26494-26502 PMID: 33020273

Biological Activity

Discription

YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1.

Targets

Target	Value

Chemical Information

Catalog Num	A11612
Formula	C17H13Cl2NO4
Molecular Weight	366.2
CAS Number	1037184-44-3
SMILES	COC1=CC=C(C=C1)C(=O)CC2(C3=C(C=CC(=C3NC2=O)Cl)Cl)O
Synonyms	YK-4-279
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	66 mg/mL (180.23 mM)
	Water	Insoluble
	Ethanol	Warmed: 46 mg/mL (125.61 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.31 mL	136.54 mL	273.07 mL
0.5 mM	5.46 mL	27.31 mL	54.61 mL
1 mM	2.73 mL	13.65 mL	27.31 mL
5 mM	0.55 mL	2.73 mL	5.46 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
YK 4-279 10mg	$60.00	In stock
YK 4-279 25mg	$120.00	In stock
YK 4-279 50mg	$200.00	In stock
*YK 4-279 10mM 1mL in DMSO**	$81.00	In stock