YK 4-279

Catalog No.: A11612

RHA inhibitor

YK 4-279

YK 4-279 Chemical Structure

CAS NO. 1037184-44-3

YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1.

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10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Christopher M Schafer, .et al. An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression, Proc Natl Acad Sci U S A, 2020, Oct 20;117(42):26494-26502 PMID: 33020273

Biological Activity

YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1.
RNA helicase A
In vitro DMSO 66 mg/mL (180.23 mM)
Water Insoluble
Ethanol Warmed: 46 mg/mL (125.61 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.31 mL 136.54 mL 273.07 mL
0.5 mM 5.46 mL 27.31 mL 54.61 mL
1 mM 2.73 mL 13.65 mL 27.31 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11612
Actions Inhibitor
CAS No. 1037184-44-3
Formula C17H13Cl2NO4
M. Wt 366.2
Purity >98%
Synonyms YK-4-279

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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