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$0.00 - Christopher M Schafer, .et al. An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression, Proc Natl Acad Sci U S A, 2020, Oct 20;117(42):26494-26502 PMID: 33020273
Biological Activity
YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1.
Targets
| RNA helicase A | ||||
| In vitro | DMSO | 66 mg/mL (180.23 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 46 mg/mL (125.61 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.31 mL | 136.54 mL | 273.07 mL |
| 0.5 mM | 5.46 mL | 27.31 mL | 54.61 mL |
| 1 mM | 2.73 mL | 13.65 mL | 27.31 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
*The above data is based on the productmolecular weight 366.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11612 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1037184-44-3 |
| Formula | C17H13Cl2NO4 |
| M. Wt | 366.2 |
| Purity | >98% |
| Synonyms | YK-4-279 |
| SMILES | COC1=CC=C(C=C1)C(=O)CC2(C3=C(C=CC(=C3NC2=O)Cl)Cl)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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