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Catalog No.: A11064

PI3K Inhibitor


YM201636 Chemical Structure

CAS NO. 371942-69-7

YM201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM).

Availability: In stock

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5 mg
10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Krishna Chintaluri, .et al. The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells, PLoS One, 2018, 13(6): e0198454 PMID: 29870544
  • Dayam RM, .et al. The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase, J Immunol, 2017, Sep 15;199(6):2096-2105 PMID: 28779020

Biological Activity

YM201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM).
PIKfyve p110α
33 nM3.3 μM
In vitro DMSO 31 mg/mL (66.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.39 mL 106.95 mL 213.9 mL
0.5 mM 4.28 mL 21.39 mL 42.78 mL
1 mM 2.14 mL 10.7 mL 21.39 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11064
Actions Inhibitor
CAS No. 371942-69-7
Formula C25H21N7O3
M. Wt 467.5
Purity >98%
Synonyms YM-201636

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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