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- Wenquan Liang, .et al. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species, Sci Rep, 2016, 6: 38267 PMID: 27905569
Biological Activity
Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.48 mL | 72.39 mL | 144.78 mL |
0.5 mM | 2.9 mL | 14.48 mL | 28.96 mL |
1 mM | 1.45 mL | 7.24 mL | 14.48 mL |
5 mM | 0.29 mL | 1.45 mL | 2.9 mL |
*The above data is based on the productmolecular weight 690.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A14358 |
---|---|
Actions | Inhibitor |
CAS No. | 210345-04-3 |
Formula | C32H43FN6O10 |
M. Wt | 690.72 |
Purity | >98% |
Synonyms | Caspase-9 Inhibitor , Z-LEHD-fluoromethylketone |
SMILES | CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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