Z-LEHD-FMK

Catalog No.: A14358

Caspase-9 Inhibitor

Z-LEHD-FMK

Z-LEHD-FMK Chemical Structure

CAS NO. 210345-04-3

Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity.

Availability: Out of stock

Package Price
1 mg
$220.00
2 mg
$400.00
5 mg
$715.00
Custom Size Get quote
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Wenquan Liang, .et al. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species, Sci Rep, 2016, 6: 38267 PMID: 27905569

Biological Activity

Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.48 mL 72.39 mL 144.78 mL
0.5 mM 2.9 mL 14.48 mL 28.96 mL
1 mM 1.45 mL 7.24 mL 14.48 mL
5 mM 0.29 mL 1.45 mL 2.9 mL

*The above data is based on the productmolecular weight 690.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14358
Actions Inhibitor
CAS No. 210345-04-3
Formula C32H43FN6O10
M. Wt 690.72
Purity >98%
Synonyms Caspase-9 Inhibitor , Z-LEHD-fluoromethylketone
SMILES CC(C)C[[email protected]@H](C(=O)N[[email protected]@H](CCC(=O)OC)C(=O)N[[email protected]@H](CC1=CN=CN1)C(=O)N[[email protected]@H](CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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