Z-LEHD-FMK

Name: Z-LEHD-FMK
Brand: Adooq Bioscience
SKU: A14358
Rating: 100 (1 reviews)

Catalog No.: A14358

Caspase-9 Inhibitor

Product Citations (1)

Z-LEHD-FMK Chemical Structure

CAS NO. 210345-04-3

Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity.

Availability: Out of stock

Package	Price
1 mg	$220.00
2 mg	$400.00
5 mg	$715.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Publications Citing Use of Adooq Z-LEHD-FMK

Wenquan Liang, .et al. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species, Sci Rep, 2016, 6: 38267 PMID: 27905569

Biological Activity

Z-LEHD-FMK is a synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.48 mL	72.39 mL	144.78 mL
0.5 mM	2.9 mL	14.48 mL	28.96 mL
1 mM	1.45 mL	7.24 mL	14.48 mL
5 mM	0.29 mL	1.45 mL	2.9 mL

*The above data is based on the productmolecular weight 690.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A14358
Actions	Inhibitor
CAS No.	210345-04-3
Formula	C32H43FN6O10
M. Wt	690.72
Purity	>98%
Synonyms	Caspase-9 Inhibitor , Z-LEHD-fluoromethylketone
SMILES	CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.