Zibotentan (ZD4054)

Catalog No.: A11006
ETA-receptor Antagonist
Zibotentan (ZD4054)is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM).
Grouped product items
Product Name Price Stock Qty
Zibotentan 5mg
In stock
Zibotentan 10mg
In stock
Zibotentan 50mg
In stock
Zibotentan 100mg
In stock
Zibotentan (ZD4054) 10mM * 1mL in DMSO
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's Zibotentan (ZD4054) has been cited by 1 publications
  • Tony Ngo, .et al. , Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882
  • Biological Activity
    Discription Zibotentan (ZD4054)is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM).
    Target Value
    Product Information
    Catalog Num A11006
    Formula C19H16N6O4S
    Molecular Weight 424.4
    CAS Number 186497-07-4
    SMILES CC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)C4=NN=CO4
    Synonyms ZD-4054

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 23 mg/mL (54.18 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.56 mL 117.81 mL 235.63 mL
    0.5 mM 4.71 mL 23.56 mL 47.13 mL
    1 mM 2.36 mL 11.78 mL 23.56 mL
    5 mM 0.47 mL 2.36 mL 4.71 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass



      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1




    • Calculator Reset
    Keywords: buy Zibotentan (ZD4054) | Zibotentan (ZD4054) Supplier | purchase Zibotentan (ZD4054) | Zibotentan (ZD4054) cost | Zibotentan (ZD4054) manufacturer | order Zibotentan (ZD4054) | Zibotentan (ZD4054) distributor | buy 186497-07-4 | 186497-07-4 Supplier | purchase 186497-07-4 | 186497-07-4 cost | 186497-07-4 manufacturer | order 186497-07-4 | 186497-07-4 distributor