Zidovudine

Catalog No.: A15428

NRTI Inhibitor

Zidovudine

Zidovudine Chemical Structure

CAS NO. 30516-87-1

Zidovudine is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. Azidothymidine decreases CRISPR-mediated homology directed repair (HDR) efficiency.

Availability: In stock

Package Price Qty
25 mg
$20.00
50 mg
$33.00
Warning WARNING: Attention California Residents: This product can expose you to chemicals including Adriamycin, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Zidovudine is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. Azidothymidine decreases CRISPR-mediated homology directed repair (HDR) efficiency.
Targets
Reverse transcriptase
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.41 mL 187.06 mL 374.11 mL
0.5 mM 7.48 mL 37.41 mL 74.82 mL
1 mM 3.74 mL 18.71 mL 37.41 mL
5 mM 0.75 mL 3.74 mL 7.48 mL

*The above data is based on the productmolecular weight 267.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15428
Actions Inhibitor
M. Wt 267.3
Formula C10H13N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 30516-87-1
Synonyms Azidothymidine, AZT, ZDV
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]

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