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Catalog No.: A11014

PI3K inhibitor


ZSTK474 Chemical Structure

CAS NO. 475110-96-4

ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.

Availability: In stock

Package Price Qty
10 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Pridham KJ, .et al. PIK3CB/p110β is a selective survival factor for glioblastoma, Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

Biological Activity

ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.
PI3Kδ (Cell-free assay) PI3Kα (Cell-free assay) PI3K (Cell-free assay) PI3Kβ (Cell-free assay) PI3Kγ (Cell-free assay)
4.6 nM16 nM37 nM44 nM49 nM
In vitro (25°C) DMSO 20 mg/mL (47.91 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% hydroxyethyl cellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.96 mL 119.79 mL 239.58 mL
0.5 mM 4.79 mL 23.96 mL 47.92 mL
1 mM 2.4 mL 11.98 mL 23.96 mL
5 mM 0.48 mL 2.4 mL 4.79 mL

*The above data is based on the productmolecular weight 417.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11014
Actions Inhibitor
CAS No. 475110-96-4
Formula C19H21F2N7O2
M. Wt 417.4
Purity >98%

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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