Product Data Sheet

Oxaliplatin (Eloxatin)

Catalog No. A10346

main product photo
Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. In vivo studies showed that Oxaliplatin has anti-tumor activity against colon carcinoma through its (non-targeted) cytotoxic effects.
Adooq's Oxaliplatin (Eloxatin) has been cited by 4 publications
  • Mohamed Elbadawy, .et al. , Biomed Pharmacother, 2021, Oct;142:112043 PMID: 34411919
  • Tatsuya Usui, .et al. , Int J Mol Sci, 2018, Apr; 19(4): 1098 PMID: 29642386
  • Shimokawa M, .et al. , Nature, 2017, May 11;545(7653):187-192 PMID: 28355176
  • Eri Takiguchi, .et al. , Exp Ther Med, 2017, Nov; 14(5): 4293-4299 PMID: 29067110
  • Chemical Information
    Catalog Num A10346
    M. Wt 397.3
    Formula C8H14N2O4Pt
    Purity >98%
    Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No. 61825-94-3
    Synonyms
    SMILES O=C3O[Pt]1(N[C@@H]2CCCC[C@H]2N1)OC3=O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Biological Activity
    Discription Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. In vivo studies showed that Oxaliplatin has anti-tumor activity against colon carcinoma through its (non-targeted) cytotoxic effects.
    Targets
    Target Value
    Solubility
    In vitro (25°C) DMSO Insoluble
    Water Warmed: 5mg/mL (5.03 mM)
    Ethanol <1 mg/mL
    In vivo 5% glucose (with warming) 2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.17 mL 125.85 mL 251.7 mL
    0.5 mM 5.03 mL 25.17 mL 50.34 mL
    1 mM 2.52 mL 12.58 mL 25.17 mL
    5 mM 0.5 mL 2.52 mL 5.03 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.