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Catalog No. Product Name Application Information
A17235
SBI-115
GPCR19 antagonist
SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.
A17219
MLS0315771
MPI inhibitor
MLS0315771 is a potent competitive phosphomannose isomerase (MPI) inhibitor.
A17238
Ro 08-2750
NGF inhibitor
Ro 08-2750 is a potent and selective Nerve growth factor (NGF) inhibitor that binds the NGF dimer (KD ~ 1 μM).
A17224
Sulfabromomethazine
Sulfabromomethazine, also known as Bromosulfamethazine, NSC 5874, SN 3517, is a long-acting derivative of sulfamezathine that is used in the poultry, swine and cattle industries for the treatment of coccidiosis.
A17242
PSMA617 TFA
PSMA-617, also know as vipivotide tetraxetan. It is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer.
A17227
AG1295
PDGFR inhibitor
AG1295 is a PDGF receptor specific inhibitor.
A17237
SAR-7334 HCl
TRPC6 inhibitor
SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected.
A17231
NUN82647
NUN82647, also known as QBS or 2-Amino-N-quinolin-8-yl-benzenesulfonamide, is an Inhibitor of cell cycle at G2 phase; apoptosis inducer.
A17230
BIBF0775
TGFβRI inhibitor
BIBF0775 is an inhibitor of the transforming growth factor β receptor I (TGFβRI).
A17228
MDL-800
SIRT6 allosteric activator
MDL-800 is a first-in-class cellularly active SIRT6 allosteric activator.
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