Product Data Sheet

6H05

Catalog No. A16097

main product photo
6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
Chemical Information
Catalog Num A16097
M. Wt 476.12
Formula C20H30ClN3O2S3
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1469338-01-9
Synonyms K-Ras inhibitor
SMILES CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC2=CC=C(C=C2)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Biological Activity
Discription 6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
Solubility
In vitro DMSO 93 mg/mL (157.59 mM)
Water 93 mg/mL (157.59 mM)
Ethanol 93 mg/mL (157.59 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21 mL 105.02 mL 210.03 mL
0.5 mM 4.2 mL 21 mL 42.01 mL
1 mM 2.1 mL 10.5 mL 21 mL
5 mM 0.42 mL 2.1 mL 4.2 mL
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.