Product Data Sheet

Cycloheximide (Actidione)

Catalog No. A10036

main product photo
Cycloheximide (also known as actidione) is used as an selective antibiotic. It inhibits the protein synthesis (DNA-dependent RNA) of saprobic fungi eukaryotes. by binding with the 80S ribosome, while inactive against dermatophytes and systemic fungi.
Adooq's Cycloheximide (Actidione) has been cited by 12 publications
  • Xiao-Yi Zhang, .et al. , Free Radic Biol Med, 2025, Aug 25:S0891-5849(25)00940-2 PMID: 40865778
  • Wan-Cheng Liu, .et al. , Nat Commun, 2025, Jun 3;16(1):5154 PMID: 40461504
  • Xingmei Shu, .et al. , Chin Med J (Engl), 2025, May 23 PMID: 40405358
  • Jing Wang, .et al. , Mol Cell, 2025, May 15;85(10):1999-2016.e11 PMID: 40328247
  • Yang Liao, .et al. , Cell Signal, 2025, Jul:131:111735 PMID: 40081551
  • Xiangdong Qiu, .et al. , Cardiovascular Toxicology, 2025, 25: 427-440
  • Tianfeng Huang, .et al. , Mol Neurobiol, 2024, Sep 13 PMID: 39271624
  • Han Xiao, .et al. , JPA, 2023, Apr 19
  • Shuanghui Lu, .et al. , Chem Biol Interact, 2022, Dec 1;368:110219 PMID: 36243147
  • Ke Chen, .et al. , Cancer Commun (Lond), 2021, Apr; 41(4): 316-332 PMID: 33591636
  • Zhiyuan Qin, .et al. , Cancers (Basel), 2021, Feb 4;13(4):618 PMID: 33557163
  • Hua Xu, .et al. , Cancers (Basel), 2020, Apr; 12(4): 831 PMID: 32235588
  • Chemical Information
    Catalog NumA10036
    M. Wt281.4
    FormulaC15H23NO4
    Purity>98%
    Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
    CAS No.66-81-9
    Synonyms
    SMILESC[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C
    Biological Activity
    DescriptionCycloheximide (also known as actidione) is used as an selective antibiotic. It inhibits the protein synthesis (DNA-dependent RNA) of saprobic fungi eukaryotes. by binding with the 80S ribosome, while inactive against dermatophytes and systemic fungi.
    Solubility
    In vitro DMSO48 mg/mL (170.61 mM)
    Water13 mg/mL (46.2 mM)
    Ethanol48 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass1 mg5 mg10 mg
    0.1 mM35.54 mL177.68 mL355.37 mL
    0.5 mM7.11 mL35.54 mL71.07 mL
    1 mM3.55 mL17.77 mL35.54 mL
    5 mM0.71 mL3.55 mL7.11 mL
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    SHIPPING AND STORAGE
    Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.